In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation

Conjugated linoleic acid (CLA) is a prime substrate for intra-gastric nitration giving rise to the formation of nitroconjugated linoleic acid (NO2-CLA). Herein, NO2-CLA generation is demonstrated within the context of acute inflammatory responses both in vitro and in vivo. Macrophage activation resu...

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Dades bibliogràfiques

Autor principal:	Villacorta, Luis (author)
Altres autors:	Minarrieta, Lucia (author), Salvatore, Sonia R. (author), Khoo, Nicholas K. (author), Rom, Oren (author), Gao, Zhen (author), Berman, Rebecca C. (author), Jobbagy, Soma (author), Li, Lihua (author), Woodcock, Steven R. (author), Chen, Y. Eugene (author), Freeman, Bruce A. (author), Ferreira, Ana M. (author), Schopfer, Francisco J. (author), Vitturi, Dario A. (author)
Format:	article
Idioma:	anglès
Publicat:	2018
Matèries:	Nitro-fatty acid Electrophile Inflammation Macrophage Nrf2 NF-κB Nitration
Accés en línia:	https://hdl.handle.net/20.500.12008/50838
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