Adipocyte-specific deletion of Dbc1 does not recapitulate healthy obesity phenotype but suggests regulation of inflammation signaling

The protein Deleted in Breast Cancer 1 (DBC1), a regulator of several transcription factors and epigenetic modulators, plays determinant roles in metabolism regulation, obesity and aging-related processes. Knockout mice for Dbc1, develop morbid obesity but are protected against liver steatosis, insu...

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Bibliographische Detailangaben

1. Verfasser:	Santos Costa, Leonardo (author)
Weitere Verfasser:	Fort Canobra, Rafael S (author), Schlapp, Geraldine (author), Cal, Karina (author), Pérez Torrado, María Valentina (author), Meikle, María Noel (author), Mulet, Ana Paula (author), Sotelo-Silveira, José Roberto (author), Verdes, José Manuel (author), Contreras Chahinian, Paola (author), Calliari Cuadro, Aldo José (author), Crispo, Martina (author), Badano, José L. (author), Escande, Carlos (author)
Format:	article
Sprache:	Englisch
Veröffentlicht:	2025
Schlagworte:	Adipocytes Mouse models Diet Genetically modified animals Obesity Adipose tissue Inflammation RNA sequencing
Online-Zugang:	https://hdl.handle.net/20.500.12008/50449
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