Activation of the NLRP3 inflammasome by particles from the Echinococcus granulosus laminated layer

The interaction of dendritic cells and macrophages with a variety ofrigid noncellular particles triggers activation of the NLRP3 inflammasome and conse-quent secretion of interleukin 1 (IL-1 ). Noncellular particles can also be generatedin the context of helminth infection, since these large pathoge...

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Bibliographic Details

Main Author:	Casaravilla, Cecilia (author)
Other Authors:	Pittini, Álvaro (author), Rückerl, Dominik (author), Allen, Judith E. (author), Díaz, Álvaro (author)
Format:	article
Language:	English
Published:	2020
Subjects:	Echinococcus Laminated layer Alum NLRP3 PI3K Membrane affinity-triggered signaling Adjuvants Dendritic cells Exophagy Helminths Inflammation Macrophages Mucin
Online Access:	https://hdl.handle.net/20.500.12008/31665
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