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Particles from the Echinococcus granulosus laminated layer inhibit IL-4 and growth factor-driven Akt phosphorylation and proliferative responses in macrophages

Proliferation of macrophages is a hallmark of inflammation in many type 2 settings including helminth infections. The cellular expansion is driven by the type 2 cytokine interleukin-4 (IL-4), as well as by M-CSF, which also controls homeostatic levels of tissue resident macrophages. Cystic echinococ...

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Hovedforfatter: Seoane, Paula I (author)
Andre forfattere: Rückerl, Dominik (author), Casaravilla, Cecilia (author), Barrios, Anabella (author), Pittini, Álvaro (author), MacDonald, Andrew S (author), Allen, Judith E. (author), Díaz, Álvaro (author)
Format: article
Sprog:engelsk
Udgivet: 2016
Fag:
Echinococcus granulosus
Helminth infections
Inflammation
Online adgang:https://hdl.handle.net/20.500.12008/22011
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https://hdl.handle.net/20.500.12008/22011

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