Particles from the Echinococcus granulosus laminated layer inhibit IL-4 and growth factor-driven Akt phosphorylation and proliferative responses in macrophages

Proliferation of macrophages is a hallmark of inflammation in many type 2 settings including helminth infections. The cellular expansion is driven by the type 2 cytokine interleukin-4 (IL-4), as well as by M-CSF, which also controls homeostatic levels of tissue resident macrophages. Cystic echinococ...

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Bibliographic Details

Main Author:	Seoane, Paula I (author)
Other Authors:	Rückerl, Dominik (author), Casaravilla, Cecilia (author), Barrios, Anabella (author), Pittini, Álvaro (author), MacDonald, Andrew S (author), Allen, Judith E. (author), Díaz, Álvaro (author)
Format:	article
Language:	English
Published:	2016
Subjects:	Echinococcus granulosus Helminth infections Inflammation
Online Access:	https://hdl.handle.net/20.500.12008/22011
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