Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis

Cells evolved robust homeostatic mechanisms to protect against oxidation or alkylation by electrophilic species. Glutathione (GSH) is the most abundant intracellular thiol, protects cellular components from oxidation and is maintained in a reduced state by glutathione reductase (GR). Nitro oleic aci...

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書誌詳細

第一著者:	Jobbagy, S. (author)
その他の著者:	Vitturi, D.A. (author), Salvatore, S.R. (author), Turell Novo, Lucía (author), Pires, M.F. (author), Kansanen, E. (author), Batthyány Dighiero, Carlos (author), Lancaster, J.R. (author), Freeman, B.A. (author), Schopfer, F.J. (author)
フォーマット:	article
言語:	英語
出版事項:	2019
主題:	Glutathione Glutathione reductase Electrophile Nitrated fatty acid Disulfide Nrf2 Thiol Oxidation-reduction (redox)
オンライン･アクセス:	https://hdl.handle.net/20.500.12008/27224
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