Acidity and nucleophilic reactivity of glutathione persulfide

Persulfides (RSSH/RSS2) participate in sulfur trafficking and metabolic processes, and are proposed to mediate the signaling effects of hydrogen sulfide (H2S). Despite their growing relevance, their chemical properties are poorly understood. Herein, we studied experimentally and computationally the...

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Bibliographic Details

Main Author:	Benchoam, Dayana (author)
Other Authors:	Semelak, Jonathan A. (author), Cuevasanta, Ernesto (author), Mastrogiovanni, Mauricio (author), Grassano, Juan S. (author), Ferrer-Sueta, Gerardo (author), Zeida, Ari (author), Trujillo, Madia (author), Möller, Matías N. (author), Estrin, Darío A (author), Álvarez, Beatriz (author)
Format:	article
Language:	English
Published:	2020
Subjects:	Enzyme mechanism Glutathione Hydrogen sulfide Persulfide Sulfhydryl Sulfur Thiol pKa α effect
Online Access:	https://hdl.handle.net/20.500.12008/26646
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