Formation of protein-derived electrophiles in ribonuclease a by biologically relevant oxidants

Oxidative modifications in proteins have been extensively studied and found to increase in diabetes, cardiovascular diseases, neurodegenerative diseases, and aging. Some of the most studied modifications include the nitration of tyrosine and the formation of carbonyls in proteins. Tyrosine can also...

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Bibliographic Details

Main Author:	López, Ana C. (author)
Other Authors:	Acosta Deccia, Silvina (author), Mastrogiovanni, Mauricio (author), Porcal, Williams (author), Portela, María Magdalena (author), Durán, Rosario (author), Radi, Rafael (author), Denicola, Ana (author), Möller, Matías N. (author)
Format:	article
Language:	English
Published:	2025
Subjects:	Free radicals Protein oxidation Tyrosine Electrophile Michael addition
Online Access:	https://hdl.handle.net/20.500.12008/54170
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