In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation

Conjugated linoleic acid (CLA) is a prime substrate for intra-gastric nitration giving rise to the formation of nitroconjugated linoleic acid (NO2-CLA). Herein, NO2-CLA generation is demonstrated within the context of acute inflammatory responses both in vitro and in vivo. Macrophage activation resu...

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Bibliographic Details

Main Author:	Villacorta, Luis (author)
Other Authors:	Minarrieta, Lucia (author), Salvatore, Sonia R. (author), Khoo, Nicholas K. (author), Rom, Oren (author), Gao, Zhen (author), Berman, Rebecca C. (author), Jobbagy, Soma (author), Li, Lihua (author), Woodcock, Steven R. (author), Chen, Y. Eugene (author), Freeman, Bruce A. (author), Ferreira, Ana M. (author), Schopfer, Francisco J. (author), Vitturi, Dario A. (author)
Format:	article
Language:	English
Published:	2018
Subjects:	Nitro-fatty acid Electrophile Inflammation Macrophage Nrf2 NF-κB Nitration
Online Access:	https://hdl.handle.net/20.500.12008/50838
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