Feasibility of a stereoselective synthesis of [11C](S, S)-S-adenosylmethionine ([11C](S,S)-SAM) catalyzed by an immobilized enzyme

This work aims to develop a stereoselective enzymatic alternative for the radiosynthesis of [11C](S,S)-S-ade-nosylmethionine ([11C](S,S)-SAM), a potential PET-CT radiotracer for monitoring particularly aggressive prostate tumors. Conventional synthesis of this compound has been carried out at Urugua...

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Bibliographic Details

Main Author:	Diego, Umpiérrez Puchalvert (author)
Other Authors:	Florencia, Zoppolo (author), Manuela Bentura (author), Agustin, Castilla (author), Eduardo, Savio (author), Sonia, Rodríguez Giordano (author), Gabriela, Irazoqui (author)
Format:	article
Language:	English
Published:	2024
Subjects:	Enzymatic radiosynthesis SAM S-adenosylmethionine Methionine adenosyltransferase Immobilized enzyme Prostate cancer radiotracer Stereospecificity Ciencias Naturales y Exactas Ciencias Químicas
Online Access:	https://hdl.handle.net/20.500.12381/5578 https://doi.org/10.1016/j.procbio.2024.12.006
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