Paternal methotrexate exposure affects sperm small RNA content and causes craniofacial defects in the offspring

Folate is an essential vitamin for vertebrate embryo development. Methotrexate (MTX) is a folate antagonist that is widely prescribed for autoimmune diseases, blood and solid organ malignancies, and dermatologic diseases. Although it is highly contraindicated for pregnant women, because it is associ...

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Үндсэн зохиолч:	Alata Jimenez, Nagif (author)
Бусад зохиолчид:	Castellano, Mauricio (author), Santillan, Emilio M. (author), Boulias, Konstantinos (author), Boan, Agustín (author), Arias Padilla, Luisa F. (author), Fernandino, Juan I. (author), Greer, Eric L. (author), Tosar Rovira, Juan Pablo (author), Cochella, Luisa (author), Strobl-Mazzulla, Pablo H. (author)
Формат:	article
Хэл сонгох:	англи
Хэвлэсэн:	2023
Нөхцлүүд:	Methotrexate Folate deficiency Sperm RNA Craniofacial defects
Онлайн хандалт:	https://hdl.handle.net/20.500.12008/42745
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!