Paternal methotrexate exposure affects sperm small RNA content and causes craniofacial defects in the offspring

Folate is an essential vitamin for vertebrate embryo development. Methotrexate (MTX) is a folate antagonist that is widely prescribed for autoimmune diseases, blood and solid organ malignancies, and dermatologic diseases. Although it is highly contraindicated for pregnant women, because it is associ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile nagusia: Alata Jimenez, Nagif (author)
Beste egile batzuk: Castellano, Mauricio (author), Santillan, Emilio M. (author), Boulias, Konstantinos (author), Boan, Agustín (author), Arias Padilla, Luisa F. (author), Fernandino, Juan I. (author), Greer, Eric L. (author), Tosar Rovira, Juan Pablo (author), Cochella, Luisa (author), Strobl-Mazzulla, Pablo H. (author)
Formatua: article
Hizkuntza:ingelesa
Argitaratua: 2023
Gaiak:
Sarrera elektronikoa:https://hdl.handle.net/20.500.12008/42745
Etiketak: Etiketa erantsi
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Antzeko izenburuak: Paternal methotrexate exposure affects sperm small RNA content and causes craniofacial defects in the offspring