Altering compositional properties of viral genomes to design Llve-attenuated vaccines

Live-attenuated vaccines have been historically used to successfully prevent numerous diseases caused by a broad variety of RNA viruses due to their ability to elicit strong and perdurable immune-protective responses. In recent years, various strategies have been explored to achieve viral attenuatio...

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Bibliografske podrobnosti

Glavni avtor:	Pereira Gómez, Marianoel (author)
Drugi avtorji:	Carrau Eguía, Lucía (author), Fajardo Rossi, Álvaro (author), Moreno Karlen, María del Pilar (author), Moratorio, Gonzalo (author)
Format:	article
Jezik:	angleščina
Izdano:	2021
Teme:	RNA viruses Genome composition Codon usage Codon pair bias Mutational robustness Attenuation, vaccines
Online dostop:	https://hdl.handle.net/20.500.12008/40941
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