Contributions of viral oncogenes of HPV‑18 and hypoxia to oxidative stress and genetic damage in human keratinocytes

Infection with high-risk human papillomaviruses like HPV-16 and HPV-18 is highly associated with the development of cervical and other cancers. Malignant transformation requires viral oncoproteins E5, E6 and E7, which promote cell proliferation and increase DNA damage. Oxidative stress and hypoxia a...

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主要作者: Hochmann Valls, Jimena (author)
其他作者: Millán Santarcieri, Magdalena (author), Hernández, Paola (author), Lafón Hughes, Laura (author), D’Aiuto, Natali (author), Silva, Alejandro (author), Llaguno, Juan (author), Alonso, Julia (author), Fernández, Ariel (author), Pereira-Prado, Vanesa (author), Sotelo-Silveira, José Roberto (author), Bologna‑Molina, Ronell (author), Arocena, Miguel (author)
格式: article
語言:英语
出版: 2023
在線閱讀:https://hdl.handle.net/20.500.12008/43179
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