Contributions of viral oncogenes of HPV‑18 and hypoxia to oxidative stress and genetic damage in human keratinocytes

Infection with high-risk human papillomaviruses like HPV-16 and HPV-18 is highly associated with the development of cervical and other cancers. Malignant transformation requires viral oncoproteins E5, E6 and E7, which promote cell proliferation and increase DNA damage. Oxidative stress and hypoxia a...

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Bibliographic Details
Main Author: Hochmann Valls, Jimena (author)
Other Authors: Millán Santarcieri, Magdalena (author), Hernández, Paola (author), Lafón Hughes, Laura (author), D’Aiuto, Natali (author), Silva, Alejandro (author), Llaguno, Juan (author), Alonso, Julia (author), Fernández, Ariel (author), Pereira-Prado, Vanesa (author), Sotelo-Silveira, José Roberto (author), Bologna‑Molina, Ronell (author), Arocena, Miguel (author)
Format: article
Language:English
Published: 2023
Online Access:https://hdl.handle.net/20.500.12008/43179
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