Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate

The protozoan parasite Trypanosoma cruzi is the causative agent of American trypanosomiasis, otherwise known as Chagas disease. To survive in the host, the T. cruzi parasite needs antioxidant defense systems. One of these is a hybrid heme peroxidase, the T. cruzi ascorbate peroxidase-cytochrome c pe...

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Dades bibliogràfiques

Autor principal:	Freeman, Samuel L. (author)
Altres autors:	Skafar Amen, Vera (author), Kwon, Hanna (author), Fielding, Alistair J. (author), Moody, Peter C. E. (author), Martínez, Alejandra (author), Issoglio, Federico M. (author), Inchausti, Lucas (author), Smircich, Pablo (author), Zeida, Ari (author), Piacenza, Lucía (author), Radi, Rafael (author), Raven, Emma L. (author)
Format:	article
Idioma:	anglès
Publicat:	2022
Matèries:	Peroxidase Chagas disease Ascorbate Cytochrome C. Heme Oxidants
Accés en línia:	https://hdl.handle.net/20.500.12008/38476
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