The pathogenic role of c‑Kit+ mast cells in the spinal motor neuron‑vascular niche in ALS

Degeneration of motor neurons, glial cell reactivity, and vascular alterations in the CNS are important neuropathological features of amyotrophic lateral sclerosis (ALS). Immune cells trafficking from the blood also infiltrate the affected CNS parenchyma and contribute to neuroinflammation. Mast cel...

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Bibliographic Details

Main Author:	Kovacs, Mariángeles (author)
Other Authors:	Alamón, Catalina (author), Maciel, Cecilia (author), Varela, Valentina (author), Ibarburu, Sofía (author), Tarrago, Lucas (author), King, Peter H. (author), Si, Ying (author), Kwon, Yuri (author), Hermine, Olivier (author), Barbeito, Luis (author), Trias, Emiliano (author)
Format:	article
Language:	English
Published:	2021
Subjects:	Mast cells Motor neuron-vascular niche ALS Masitinib Spinal cord
Online Access:	https://hdl.handle.net/20.500.12008/37418
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