The pathogenic role of c‑Kit+ mast cells in the spinal motor neuron‑vascular niche in ALS

Degeneration of motor neurons, glial cell reactivity, and vascular alterations in the CNS are important neuropathological features of amyotrophic lateral sclerosis (ALS). Immune cells trafficking from the blood also infiltrate the affected CNS parenchyma and contribute to neuroinflammation. Mast cel...

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Dettagli Bibliografici

Autore principale:	Kovacs, Mariángeles (author)
Altri autori:	Alamón, Catalina (author), Maciel, Cecilia (author), Varela, Valentina (author), Ibarburu, Sofía (author), Tarrago, Lucas (author), King, Peter H. (author), Si, Ying (author), Kwon, Yuri (author), Hermine, Olivier (author), Barbeito, Luis (author), Trias, Emiliano (author)
Natura:	article
Lingua:	inglese
Pubblicazione:	2021
Soggetti:	Mast cells Motor neuron-vascular niche ALS Masitinib Spinal cord
Accesso online:	https://hdl.handle.net/20.500.12008/37418
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