The short-sequence design of DNA and its involvement in the 3-D structure of the genome

Recent investigations have shown that isochores are characterized by a 3-D structure which is primarily responsible for the topology of chromatin domains. More precisely, an analysis of human chromosome 21 demonstrated that low-heterogeneity, GC-poor isochores are characterized by the presence of ol...

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Bibliographic Details
Main Author: Lamolle, Guillermo (author)
Other Authors: Sabbia Carriquiry, Victor Manuel (author), Musto, Héctor (author), Bernardi, Giorgio (author)
Format: article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/20.500.12008/22004
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