SOD1G93A Astrocyte-Derived Extracellular Vesicles Induce Motor Neuron Death by a miRNA-155-5p-Mediated Mechanism

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by upper and lower motor neuron (MN) degeneration. Astrocytes surrounding MNs are known to modulate ALS progression. When cocultured with astrocytes overexpressing the ALS-linked mutant Cu/Zn superoxide dismutase...

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Bibliographic Details

Main Author:	Marton, Soledad (author)
Other Authors:	Miquel, Ernesto (author), Acosta-Rodríguez, Joaquín (author), Fontenla, Santiago (author), Libisch, Gabriela (author), Cassina, Patricia (author)
Format:	article
Language:	English
Published:	2023
Subjects:	ALS Astrocytes Exosomes microRNA miR-155-5p Motor neuron GENÉTICA ESCLEROSIS AMIOTRÓFICA LATERAL METABOLISMO ANIMALES ASTROCITOS MODELOS ANIMALES DE ENFERMEDAD VESÍCULAS EXTRACELULARES RATONES TRANSGÉNICOS MICROARNs NEURONAS MOTORAS SUPERÓXIDO DISMUTASA-1 ENFERMEDADES NEURODEGENERATIVAS
Online Access:	https://hdl.handle.net/20.500.12008/53317
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