Tacrolimus pharmacodynamics and pharmacogenetics along the calcineurin pathway in human lymphocytes.

BACKGROUND: Although therapeutic drug monitoring has improved the clinical use of immunosuppressive drugs, there is still interpatient variability in efficacy and toxicity that pharmacodynamic monitoring may help to reduce. To select the best biomarkers of tacrolimus pharmacodynamics, we explored th...

Ausführliche Beschreibung

Bibliographische Detailangaben

1. Verfasser:	Noceti, Ofelia (author)
Weitere Verfasser:	Woillard, Jean-Baptiste (author), Boumediene, Ahmed (author), Esperón, Patricia (author), Taupin, Jean-Luc (author), Gerona, Solange (author), Valverde, Marcelo (author), Touriño, Cristina (author), Marquet, Pierre (author)
Format:	article
Sprache:	Englisch
Veröffentlicht:	2014
Schlagworte:	Organ transplantation Calcineurin inhibitor agents Nuclear factor of activated T cells Interleukin 2 CD25 Ciencias Médicas y de la Salud Medicina Básica Farmacología y Farmacia Biotecnología de la Salud Tecnologías que involucran la manipulación de células, tejidos, órganos o todo el org Medicina Clínica Transplantes
Online-Zugang:	http://hdl.handle.net/20.500.12381/199
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