Tacrolimus pharmacodynamics and pharmacogenetics along the calcineurin pathway in human lymphocytes.

BACKGROUND: Although therapeutic drug monitoring has improved the clinical use of immunosuppressive drugs, there is still interpatient variability in efficacy and toxicity that pharmacodynamic monitoring may help to reduce. To select the best biomarkers of tacrolimus pharmacodynamics, we explored th...

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Bibliographic Details

Main Author:	Noceti, Ofelia (author)
Other Authors:	Woillard, Jean-Baptiste (author), Boumediene, Ahmed (author), Esperón, Patricia (author), Taupin, Jean-Luc (author), Gerona, Solange (author), Valverde, Marcelo (author), Touriño, Cristina (author), Marquet, Pierre (author)
Format:	article
Language:	English
Published:	2014
Subjects:	Organ transplantation Calcineurin inhibitor agents Nuclear factor of activated T cells Interleukin 2 CD25 Ciencias Médicas y de la Salud Medicina Básica Farmacología y Farmacia Biotecnología de la Salud Tecnologías que involucran la manipulación de células, tejidos, órganos o todo el org Medicina Clínica Transplantes
Online Access:	http://hdl.handle.net/20.500.12381/199
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