Looking for approved-medicines to be repositioned as anti-Trypanosoma cruzi agents. Identification of new chemotypes with good individual- or in combination-biological behaviours

BACKGROUND The neglected illness Chagas disease is treated with limited efficacy and adverse effects by old drugs. Due to the low interest of pharmaceutical industry in targeting economically depressed-patients, repurposing is a tool that should be applied because it can introduce new anti-Chagas en...

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Bibliographic Details

Main Author:	Veira, Claudia (author)
Other Authors:	Benítez, Diego (author), Pérez Díaz, Leticia (author), Álvarez, Guzmán (author), Cerecetto, Hugo (author), Aguilera, Elena (author)
Format:	article
Language:	English
Published:	2025
Subjects:	Chagas disease Medicines-repositioning Isobologram Synergism - additivity
Online Access:	https://hdl.handle.net/20.500.12008/53058
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