Characteristics of Mycobacterium tuberculosis PtpA interaction and activity on the alpha subunit of human mitochondrial trifunctional protein, a key enzyme of lipid metabolism

During Mycobacterium tuberculosis (Mtb) infection, the virulence factor PtpA belonging to the protein tyrosine phosphatase family is delivered into the cytosol of the macrophage. PtpA interacts with numerous eukaryotic proteins modulating phagosome maturation, innate immune response, apoptosis, and...

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Bibliographic Details
Main Author: Margenat, Mariana (author)
Other Authors: Betancour Curutchet, Gabriela (author), Irving, Vivian (author), Costábile Cristech, Alicia (author), García Cedrés, Tania (author), Portela, María Magdalena (author), Carrión Runco, Federico Daniel (author), Herrera, Fernando E. (author), Villarino, Andrea (author)
Format: article
Language:English
Published: 2023
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Online Access:https://hdl.handle.net/20.500.12008/43100
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