PDCD4 regulates axonal growth by translational repression of neurite growth-related genes and is modulated during nerve injury responses

Programmed Cell Death 4 (PDCD4) protein is a tumour suppressor that inhibits translation through the mTOR dependent initiation factor EIF4A, but its functional role and mRNA targets in neurons remain largely unknown. Our work identified that PDCD4 is highly expressed in axons and dendrites of CNS an...

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Opis bibliograficzny

1. autor:	Di Paolo, Andrés (author)
Kolejni autorzy:	Eastman, Guillermo (author), Mesquita-Ribeiro, R. (author), Farías, Joaquina (author), Macklin, A. (author), Kislingerd, T. (author), Colburn, N. (author), Munroe, D. J. (author), Sotelo Sosa, José Roberto (author), Dajas-Bailador, F. (author), Sotelo-Silveira, José Roberto (author)
Format:	article
Język:	angielski
Wydane:	2020
Hasła przedmiotowe:	Programmed Cell Death 4 (PDCD4) Axonal growth Axonal regeneration Ribosome profiling Translation
Dostęp online:	https://hdl.handle.net/20.500.12008/31761
Etykiety:	Dodaj etykietę Nie ma etykietki, Dołącz pierwszą etykiete!