PDCD4 regulates axonal growth by translational repression of neurite growth-related genes and is modulated during nerve injury responses

Programmed Cell Death 4 (PDCD4) protein is a tumour suppressor that inhibits translation through the mTOR dependent initiation factor EIF4A, but its functional role and mRNA targets in neurons remain largely unknown. Our work identified that PDCD4 is highly expressed in axons and dendrites of CNS an...

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Detalles Bibliográficos

Autor Principal:	Di Paolo, Andrés (author)
Outros autores:	Eastman, Guillermo (author), Mesquita-Ribeiro, R. (author), Farías, Joaquina (author), Macklin, A. (author), Kislingerd, T. (author), Colburn, N. (author), Munroe, D. J. (author), Sotelo Sosa, José Roberto (author), Dajas-Bailador, F. (author), Sotelo-Silveira, José Roberto (author)
Formato:	article
Idioma:	inglés
Publicado:	2020
Subjects:	Programmed Cell Death 4 (PDCD4) Axonal growth Axonal regeneration Ribosome profiling Translation
Acceso en liña:	https://hdl.handle.net/20.500.12008/31761
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