Kinetic studies reveal a key role of a redox-active glutaredoxin in the evolution of the thiol-redox metabolism of trypanosomatid parasites

Trypanosomes are flagellated protozoan parasites (kinetoplastids) that have a unique redox metabolism based on the small dithiol trypanothione (T(SH)2). Although GSH may still play a biological role in trypanosomatid parasites beyond being a building block of T(SH)2, most of its functions are replac...

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Bibliographic Details

Main Author:	Manta, Bruno (author)
Other Authors:	Möller, Matías N. (author), Bonilla Chao, Mariana Magdalena (author), Deambrosi Borrat, Matías (author), Grunberg, Karin (author), Bellanda, M. (author), Comini, Marcelo A. (author), Ferrer-Sueta, Gerardo (author)
Format:	article
Language:	English
Published:	2019
Subjects:	Trypanosome Glutathionylation Oxidation-reduction (redox) Enzyme catalysis Disulfide Thiol Fluorescence Trypanothione
Online Access:	https://hdl.handle.net/20.500.12008/27635
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