Stafne’s bone defect: a systematic review

Background: This systematic review integrated the available data published in the literature on Stafne’s bone defect (SBD), considering the clinical, imaging and histopathological results. Material and Methods: An electronic search was undertaken in six databases. Eligibility criteria were: articles...

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Autore principale: Alini, Soares (author)
Altri autori: Luíse, Ferreira (author), Camila, Calderipe (author), Bologna-Molina, Ronell (author), Damian, Melissa (author), Martins, Manoela Domingues (author), Silveira, Felipe Martins (author), Vasconcelos, Ana Carolina (author)
Natura: article
Lingua:inglese
Pubblicazione: 2023
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Accesso online:https://hdl.handle.net/20.500.12008/42888
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Riassunto:Background: This systematic review integrated the available data published in the literature on Stafne’s bone defect (SBD), considering the clinical, imaging and histopathological results. Material and Methods: An electronic search was undertaken in six databases. Eligibility criteria were: articles in English, Spanish, and Portuguese describing case reports or case series of SBD, reported up to September/2021. Risk of bias was assessed using the Joanna Briggs Institute tool. Results: A total of 98 articles were retrieved, involving 465 individuals with SBD and were included for quantitative analysis. Mean age was 52.78 years (range: 11-89 years), with male predilection (n=374/80.85%). Radiographs were the most frequent imagiological exams (n=298/64.09%), followed by computed tomography (n=98/21.08%). SBD was more prevalent in the posterior mandible (n=361/93.77%) as a hypodense radiolucent lesion (n=250/77.40%). Mean size was 1.58 cm (range: 0.3-.8.0 cm). Two-hundred-and-two lesions (97.37%) were unilocular and 126 (91.97%) were classified as well-defined. Clinical symptoms were reported in 73 cases, while 68 cases (93.15%) were asymptomatic. Only 34 cases (12.32%) were submitted to histopathological examination. Mean follow-up time was 26.42 ±25.39 months. Conclusions: SBD is more frequent in male patients in the fifth and sixth decade of life. Classic SBD is radiographically characterized as a single, unilocular and well-defined lesion in the posterior region of the jaw with a radiolucent/hypodense appearance