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Mitochondrial Peroxiredoxin 3 Is Rapidly Oxidized and Hyperoxidized by Fatty Acid Hydroperoxides

Human peroxiredoxin 3 (HsPrx3) is a thiol-based peroxidase responsible for the reduction of most hydrogen peroxide and peroxynitrite formed in mitochondria. Mitochondrial disfunction can lead to membrane lipoperoxidation, resulting in the formation of lipid-bound fatty acid hydroperoxides (LFA-OOHs)...

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Hovedforfatter: Cardozo, Giuliana (author)
Andre forfattere: Mastrogiovanni, Mauricio (author), Zeida, Ari (author), Viera, Nicolás (author), Radi, Rafael (author), Reyes, Aníbal M. (author), Trujillo, Maida (author)
Format: article
Sprog:engelsk
Udgivet: 2023
Fag:
Antioxidant systems
Fatty acid hydroperoxide
Kinetics
Lipid peroxidation
Mitochondria
Peroxiredoxin
PEROXIRREDOXINAS
PERÓXIDO DE HIDRÓGENO
ÁCIDO PEROXINITROSO
MITOCONDRIAS
PERÓXIDOS LIPÍDICOS
CINÉTICA
PEROXIDACIÓN DE LÍPIDO
Online adgang:https://hdl.handle.net/20.500.12008/52239
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https://hdl.handle.net/20.500.12008/52239

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