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Molecular accuracy vs antigenic speed: SARS-CoV-2 testing strategies

The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has hit every corner of the world faster than any infectious disease ever known. In this context, rapid and accurate testing of positive cases are essential to follow the test-trace-isolate strategy (TETRIS), whi...

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Hlavní autor: Fajardo, Álvaro (author)
Další autoři: Perbolianachis, Paula (author), Ferreiro, Irene (author), Moreno, Pilar (author), Moratorio, Gonzalo (author)
Médium: article
Jazyk:angličtina
Vydáno: 2021
Témata:
SARS-CoV-2
Testing strategies
RT-PCR
Antigenic test
Ciencias Naturales y Exactas
Ciencias Biológicas
Virología
On-line přístup:https://hdl.handle.net/20.500.12381/3466
https://doi.org/10.1016/j.coph.2021.12.006
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Shrnutí:The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has hit every corner of the world faster than any infectious disease ever known. In this context, rapid and accurate testing of positive cases are essential to follow the test-trace-isolate strategy (TETRIS), which has proven to be a key approach to constrain viral spread. Here, we discuss how to interpret and combine molecular or/and antigen-based detection methods for SARS-CoV-2 as well as when they should be used. Their application can be cleverly designed as an algorithm to prevent viral dissemination according to distinct epidemiological contexts within surveillance programs.

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