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Human papillomavirus type 18 E5 oncoprotein cooperates with E6 and E7 in promoting cell viability and invasion and in modulating the cellular redox state

BACKGROUND High-risk human papillomaviruses (HR-HPVs) are the etiological agents of cervical cancer. Among them, types 16 and 18 are the most prevalent worldwide. The HPV genome encodes three oncoproteins (E5, E6, and E7) that possess a high transformation potential in culture cells when transduced...

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Main Author: Hochmann Valls, Jimena (author)
Other Authors: Parietti, Felipe (author), Martínez, Jennyfer (author), López Royes, Ana Clara (author), Carreño Sastre, Mara (author), Quijano, Celia (author), Boccardo, Enrique (author), Sichero, Laura (author), Möller, Matías N. (author), Mirazo, Santiago (author), Arbiza, Juan (author)
Format: article
Language:English
Published: 2020
Subjects:
HPV-18 E5/E6/E7
Cooperation
Cell invasion
Redox state
Cellular transformation
Reactive oxygen species
Online Access:https://hdl.handle.net/20.500.12008/31730
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https://hdl.handle.net/20.500.12008/31730

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