A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditions
Background: Insulin-like growth factor 1 (IGF-1) gene is considered as a promising candidate for the identification of polymorphisms affecting cattle performance. The objectives of the current study were to determine the association of the single nucleotide polymorphism (SNP) IGF-1/SnaBI with fertil...
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| Drugi avtorji: | , |
| Format: | article |
| Jezik: | angleščina |
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2013
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| Online dostop: | https://hdl.handle.net/20.500.12008/50664 https://doi.org/10.1186/1751-0147-55-11 |
| Oznake: |
Brez oznak, prvi označite!
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| _version_ | 1868890177357742080 |
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| author | Nicolini, Paula |
| author2 | Carriquiry Fossemale, Mariana Meikle, Ana |
| author2_role | author author |
| author_browse | Carriquiry Fossemale, Mariana Meikle, Ana Nicolini, Paula |
| author_facet | Nicolini, Paula Carriquiry Fossemale, Mariana Meikle, Ana |
| author_role | author |
| collection | COLIBRI |
| dc.contributor.none.fl_str_mv | Nicolini Paula, University of Republic (Uruguay). Faculty of Veterinary Medicine. Laboratory of Nuclear Techniques Carriquiry Fossemale Mariana, University of Uruguay (Uruguay). Faculty of Agronomy Sciences Meikle Ana, University of Republic (Uruguay). Faculty of Veterinary Medicine. Laboratory of Nuclear Techniques |
| dc.creator.none.fl_str_mv | Nicolini, Paula Carriquiry Fossemale, Mariana Meikle, Ana |
| dc.date.none.fl_str_mv | 2013 2025-07-17T13:02:09Z 2025-07-17T13:02:09Z |
| dc.format.none.fl_str_mv | 8 p application/pdf |
| dc.identifier.none.fl_str_mv | Nicolini, P, Carriquiry Fossemale, M y Meikle, A. A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditions. Acta Veterinaria Scandinavica. [en línea] 2013, 55(11), 1-8 https://hdl.handle.net/20.500.12008/50664 https://doi.org/10.1186/1751-0147-55-11 |
| dc.language.none.fl_str_mv | en eng |
| dc.relation.none.fl_str_mv | Acta Veterinaria Scandinavica, 2013, 55(11), 1-8 |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess Licencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0) |
| dc.source.none.fl_str_mv | reponame:COLIBRI instname:Universidad de la República instacron:Universidad de la República |
| dc.subject.none.fl_str_mv | BOVINOS VACAS LECHERAS PRODUCCION LECHERA PASTOREO FERTILIDAD |
| dc.title.none.fl_str_mv | A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditions |
| dc.type.none.fl_str_mv | Artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| description | Background: Insulin-like growth factor 1 (IGF-1) gene is considered as a promising candidate for the identification of polymorphisms affecting cattle performance. The objectives of the current study were to determine the association of the single nucleotide polymorphism (SNP) IGF-1/SnaBI with fertility, milk production and body condition traits in Holstein-Friesian dairy cows under grazing conditions. Methods: Seventy multiparous cows from a commercial herd were genotyped for the SNP IGF-1/SnaBI. Fertility measures evaluated were: interval to commencement of luteal activity (CLA), calving to first service (CFS) and calving to conception (CC) intervals. Milk production and body condition score were also evaluated. The study period extended from 3 wk before calving to the fourth month of lactation. Results and discussion: Frequencies of the SNP IGF-1/SnaBI alleles A and B were 0.59 and 0.41, respectively. Genotype frequencies were 0.31, 0.54 and 0.14 for AA, AB and BB, respectively. Cows with the AA genotype presented an early CLA and were more likely to resume ovarian cyclicity in the early postpartum than AB and BB ones. No effect of the SNP IGF-1/SnaBI genotype was evidenced on body condition change over the experimental period, suggesting that energy balance is not responsible for the outcome of postpartum ovarian resumption in this study. Traditional fertility measures were not affected by the SNP IGF-1/SnaBI. Conclusion: To our knowledge this is the first report describing an association of the SNP IGF-1/SnaBI with an endocrine fertility measure like CLA in cattle. Results herein remark the important role of the IGF-1gene in the fertility of dairy cows on early lactation and make the SNP IGF-1/SnaBI an interesting candidate marker for genetic improvement of fertility in dairy cattle. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | anni_bbbb0063012b693e8d89afb8096e66da |
| identifier_str_mv | Nicolini, P, Carriquiry Fossemale, M y Meikle, A. A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditions. Acta Veterinaria Scandinavica. [en línea] 2013, 55(11), 1-8 |
| instacron_str | Universidad de la República |
| institution | Universidad de la República |
| instname_str | Universidad de la República |
| language | eng |
| language_invalid_str_mv | en |
| network_acronym_str | anni |
| network_name_str | oai-lr-anni |
| oai_identifier_str | oai:colibri.udelar.edu.uy:20.500.12008/50664 |
| publishDate | 2013 |
| publishDateSort | 2013 |
| reponame_str | COLIBRI |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | Licencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0) |
| spelling | A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditionsNicolini, PaulaCarriquiry Fossemale, MarianaMeikle, AnaBOVINOSVACAS LECHERASPRODUCCION LECHERAPASTOREOFERTILIDADBackground: Insulin-like growth factor 1 (IGF-1) gene is considered as a promising candidate for the identification of polymorphisms affecting cattle performance. The objectives of the current study were to determine the association of the single nucleotide polymorphism (SNP) IGF-1/SnaBI with fertility, milk production and body condition traits in Holstein-Friesian dairy cows under grazing conditions. Methods: Seventy multiparous cows from a commercial herd were genotyped for the SNP IGF-1/SnaBI. Fertility measures evaluated were: interval to commencement of luteal activity (CLA), calving to first service (CFS) and calving to conception (CC) intervals. Milk production and body condition score were also evaluated. The study period extended from 3 wk before calving to the fourth month of lactation. Results and discussion: Frequencies of the SNP IGF-1/SnaBI alleles A and B were 0.59 and 0.41, respectively. Genotype frequencies were 0.31, 0.54 and 0.14 for AA, AB and BB, respectively. Cows with the AA genotype presented an early CLA and were more likely to resume ovarian cyclicity in the early postpartum than AB and BB ones. No effect of the SNP IGF-1/SnaBI genotype was evidenced on body condition change over the experimental period, suggesting that energy balance is not responsible for the outcome of postpartum ovarian resumption in this study. Traditional fertility measures were not affected by the SNP IGF-1/SnaBI. Conclusion: To our knowledge this is the first report describing an association of the SNP IGF-1/SnaBI with an endocrine fertility measure like CLA in cattle. Results herein remark the important role of the IGF-1gene in the fertility of dairy cows on early lactation and make the SNP IGF-1/SnaBI an interesting candidate marker for genetic improvement of fertility in dairy cattle.Nicolini Paula, University of Republic (Uruguay). Faculty of Veterinary Medicine. Laboratory of Nuclear TechniquesCarriquiry Fossemale Mariana, University of Uruguay (Uruguay). Faculty of Agronomy SciencesMeikle Ana, University of Republic (Uruguay). Faculty of Veterinary Medicine. Laboratory of Nuclear Techniques2025-07-17T13:02:09Z2025-07-17T13:02:09Z2013Artículoinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion8 papplication/pdfNicolini, P, Carriquiry Fossemale, M y Meikle, A. A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditions. Acta Veterinaria Scandinavica. [en línea] 2013, 55(11), 1-8https://hdl.handle.net/20.500.12008/50664https://doi.org/10.1186/1751-0147-55-11reponame:COLIBRIinstname:Universidad de la Repúblicainstacron:Universidad de la RepúblicaenengActa Veterinaria Scandinavica, 2013, 55(11), 1-8Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014)info:eu-repo/semantics/openAccessLicencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0)oai:colibri.udelar.edu.uy:20.500.12008/506642026-04-14T10:35:07Z |
| spellingShingle | A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditions Nicolini, Paula BOVINOS VACAS LECHERAS PRODUCCION LECHERA PASTOREO FERTILIDAD |
| status_str | publishedVersion |
| title | A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditions |
| title_full | A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditions |
| title_fullStr | A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditions |
| title_full_unstemmed | A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditions |
| title_short | A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditions |
| title_sort | A polymorphism in the insulin-like growth factor 1 gene is associated with postpartum resumption of ovarian cyclicity in Holstein-Friesian cows under grazing conditions |
| topic | BOVINOS VACAS LECHERAS PRODUCCION LECHERA PASTOREO FERTILIDAD |
| url | https://hdl.handle.net/20.500.12008/50664 https://doi.org/10.1186/1751-0147-55-11 |