Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic Review
Abstract: Periodontal disease (PD) and obesity are characterized by a dysregulated inflammatory state. Both conditions trigger inflammatory and immune responses with an increase in proinflammatory cytokines such as Interleukin 6 (IL-6) and the release of inflammatory mediators such as C-reactive pro...
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| Format: | article |
| Language: | English |
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2022
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| Online Access: | https://hdl.handle.net/20.500.12008/35194 |
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| _version_ | 1868890146795945984 |
|---|---|
| author | Cruz Ávila, Julieta |
| author2 | Hernández Pérez, Elizabeth González González, Rogelio Bologna-Molina, Ronell Molina-Frechero, Nelly |
| author2_role | author author author author |
| author_browse | Bologna-Molina, Ronell Cruz Ávila, Julieta González González, Rogelio Hernández Pérez, Elizabeth Molina-Frechero, Nelly |
| author_facet | Cruz Ávila, Julieta Hernández Pérez, Elizabeth González González, Rogelio Bologna-Molina, Ronell Molina-Frechero, Nelly |
| author_role | author |
| collection | COLIBRI |
| dc.contributor.none.fl_str_mv | Cruz Ávila Julieta, Dental Sciences, Department of Health Care, Universidad Autónoma Metropolitana Xochimilco Hernández Pérez Elizabeth, Department of Health Sciences, Universidad Autónoma Metropolitana Iztapalapa González González Rogelio, Department of Research, School of Dentistry, Juarez University of the Durango State Bologna Molina Ronell, Molecular Pathology Area, School of Dentistry, University of the Republic Molina Frechero Nelly, Department of Health Care, Universidad Autónoma Metropolitana Xochimilco |
| dc.creator.none.fl_str_mv | Cruz Ávila, Julieta Hernández Pérez, Elizabeth González González, Rogelio Bologna-Molina, Ronell Molina-Frechero, Nelly |
| dc.date.none.fl_str_mv | 2022-12-08T13:01:06Z 2022-12-08T13:01:06Z 2022 |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | Cruz Ávila, J, Hernández Pérez, E, González González, R. y otros "Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic Review". Dent. J. [en línea] 2022 Vol. 10(12), 225 .doi.org/10.3390/dj10120225 https://hdl.handle.net/20.500.12008/35194 doi.org/10.3390/dj10120225 |
| dc.language.none.fl_str_mv | en eng |
| dc.relation.none.fl_str_mv | Dent. J. 2022, Vol. 10(12), 225 |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess Licencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0) |
| dc.source.none.fl_str_mv | reponame:COLIBRI instname:Universidad de la República instacron:Universidad de la República |
| dc.subject.none.fl_str_mv | IL-6 Periodontal disease Obesity C-reactive protein ENFERMEDADES PERIODONTALES OBESIDAD INTERLEUCINA-6 PROTEINA C REACTIVA |
| dc.title.none.fl_str_mv | Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic Review |
| dc.type.none.fl_str_mv | Artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| description | Abstract: Periodontal disease (PD) and obesity are characterized by a dysregulated inflammatory state. Both conditions trigger inflammatory and immune responses with an increase in proinflammatory cytokines such as Interleukin 6 (IL-6) and the release of inflammatory mediators such as C-reactive protein (CRP). Individuals with a high body mass index (BMI) present a chronic inflammatory state. The aim of the present study was to perform a systematic review of inflammatory markers (IL-6 and CRP) in obese patients with PD and their possible relationship by analyzing the levels of these markers. A digital literature search was performed in three databases—PubMed, SciElo and Medigraphic—through an advanced search for original articles, employing IL-6 and CRP in obese patients with PD, within a publication period from 2010 to 2021. PRISMA guidelines, the JADAD scale and a qualitative analysis of scientific evidence were performed using the Cochrane collaboration method and the RoB 2 assessment tool. Ten articles were included in this analysis with the variables recorded and associated with subjects with obesity and PD. Of the ten articles included, three analyzed IL-6 and CRP, four analyzed IL-6 and three analyzed CRP. In conclusion, and based on the available evidence, the aforementioned markers of inflammation demonstrate that there is a relationship between PD and obesity. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | anni_9dec7e994b6b87ee7f2674e1fcaa1f01 |
| identifier_str_mv | Cruz Ávila, J, Hernández Pérez, E, González González, R. y otros "Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic Review". Dent. J. [en línea] 2022 Vol. 10(12), 225 .doi.org/10.3390/dj10120225 doi.org/10.3390/dj10120225 |
| instacron_str | Universidad de la República |
| institution | Universidad de la República |
| instname_str | Universidad de la República |
| language | eng |
| language_invalid_str_mv | en |
| network_acronym_str | anni |
| network_name_str | oai-lr-anni |
| oai_identifier_str | oai:colibri.udelar.edu.uy:20.500.12008/35194 |
| publishDate | 2022 |
| publishDateSort | 2022 |
| reponame_str | COLIBRI |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | Licencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0) |
| spelling | Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic ReviewCruz Ávila, JulietaHernández Pérez, ElizabethGonzález González, RogelioBologna-Molina, RonellMolina-Frechero, NellyIL-6Periodontal diseaseObesityC-reactive proteinENFERMEDADES PERIODONTALESOBESIDADINTERLEUCINA-6PROTEINA C REACTIVAAbstract: Periodontal disease (PD) and obesity are characterized by a dysregulated inflammatory state. Both conditions trigger inflammatory and immune responses with an increase in proinflammatory cytokines such as Interleukin 6 (IL-6) and the release of inflammatory mediators such as C-reactive protein (CRP). Individuals with a high body mass index (BMI) present a chronic inflammatory state. The aim of the present study was to perform a systematic review of inflammatory markers (IL-6 and CRP) in obese patients with PD and their possible relationship by analyzing the levels of these markers. A digital literature search was performed in three databases—PubMed, SciElo and Medigraphic—through an advanced search for original articles, employing IL-6 and CRP in obese patients with PD, within a publication period from 2010 to 2021. PRISMA guidelines, the JADAD scale and a qualitative analysis of scientific evidence were performed using the Cochrane collaboration method and the RoB 2 assessment tool. Ten articles were included in this analysis with the variables recorded and associated with subjects with obesity and PD. Of the ten articles included, three analyzed IL-6 and CRP, four analyzed IL-6 and three analyzed CRP. In conclusion, and based on the available evidence, the aforementioned markers of inflammation demonstrate that there is a relationship between PD and obesity.Cruz Ávila Julieta, Dental Sciences, Department of Health Care, Universidad Autónoma Metropolitana XochimilcoHernández Pérez Elizabeth, Department of Health Sciences, Universidad Autónoma Metropolitana IztapalapaGonzález González Rogelio, Department of Research, School of Dentistry, Juarez University of the Durango StateBologna Molina Ronell, Molecular Pathology Area, School of Dentistry, University of the RepublicMolina Frechero Nelly, Department of Health Care, Universidad Autónoma Metropolitana Xochimilco2022-12-08T13:01:06Z2022-12-08T13:01:06Z2022Artículoinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfCruz Ávila, J, Hernández Pérez, E, González González, R. y otros "Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic Review". Dent. J. [en línea] 2022 Vol. 10(12), 225 .doi.org/10.3390/dj10120225https://hdl.handle.net/20.500.12008/35194doi.org/10.3390/dj10120225reponame:COLIBRIinstname:Universidad de la Repúblicainstacron:Universidad de la RepúblicaenengDent. J. 2022, Vol. 10(12), 225Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014)info:eu-repo/semantics/openAccessLicencia Creative Commons Atribución - No Comercial (CC - By-NC 4.0)oai:colibri.udelar.edu.uy:20.500.12008/351942026-04-14T10:37:13Z |
| spellingShingle | Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic Review Cruz Ávila, Julieta IL-6 Periodontal disease Obesity C-reactive protein ENFERMEDADES PERIODONTALES OBESIDAD INTERLEUCINA-6 PROTEINA C REACTIVA |
| status_str | publishedVersion |
| title | Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic Review |
| title_full | Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic Review |
| title_fullStr | Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic Review |
| title_full_unstemmed | Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic Review |
| title_short | Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic Review |
| title_sort | Periodontal Disease in Obese Patients; Interleukin-6 and C-Reactive Protein Study: A Systematic Review |
| topic | IL-6 Periodontal disease Obesity C-reactive protein ENFERMEDADES PERIODONTALES OBESIDAD INTERLEUCINA-6 PROTEINA C REACTIVA |
| url | https://hdl.handle.net/20.500.12008/35194 |