Multi-anti-parasitic activity of arylidene ketones and thiazolidene hydrazines against trypanosoma cruzi and Leishmania spp.

A series of fifty arylideneketones and thiazolidenehydrazines was evaluated against Leishmania infantum and Leishmania braziliensis. Furthermore, new simplified thiazolidenehydrazine derivatives were evaluated against Trypanosoma cruzi. The cytotoxicity of the active compounds on non-infected fibrob...

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Bibliographic Details

Main Author:	Álvarez, Guzmán (author)
Other Authors:	Perdomo, Cintya (author), Coronel, Cathia (author), Aguilera, Elena (author), Varela, Javier (author), Aparicio Díaz, Hector Gonzalo (author), Zolessi, Flavio R. (author), Cabrera, Nallely (author), Vega, Celeste (author), Rolón, Miriam (author), Rojas de Arias, Antonieta (author), Pérez-Montfort, Ruy (author), Cerecetto, Hugo (author), González, Mercedes (author)
Format:	article
Language:	English
Published:	2017
Subjects:	Anti-T. cruzi and anti-Leishmania spp. activity Arylidene ketones Thiazolidene hydrazines Triosephosphate isomerase Cruzipain In vivo toxicity Zebrafish
Online Access:	https://hdl.handle.net/20.500.12008/35753
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