A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world
Since its first detection in the UK in September 2020, a highly contagious version of the coronavirus, the alpha or British variant a.k.a. B.1.1.7 SARS-CoV-2 virus lineage, rapidly spread across several countries and became the dominant strain in the outbreak. Here it is shown that a very simple evo...
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| Format: | article |
| Language: | English |
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2021
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| Online Access: | https://hdl.handle.net/20.500.12008/33428 |
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| _version_ | 1868890133424504832 |
|---|---|
| author | Fort, Hugo |
| author_browse | Fort, Hugo |
| author_facet | Fort, Hugo |
| author_role | author |
| collection | COLIBRI |
| dc.contributor.none.fl_str_mv | Fort Hugo, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física. |
| dc.creator.none.fl_str_mv | Fort, Hugo |
| dc.date.none.fl_str_mv | 2021 2022-08-30T14:08:18Z 2022-08-30T14:08:18Z |
| dc.format.none.fl_str_mv | 5 h application/pdf |
| dc.identifier.none.fl_str_mv | Fort, H. "A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world". Virus Research. [en línea] 2021, 304: 198531. 5 h. Doi: 10.1016/j.virusres.2021.198531. 0168-1702 https://hdl.handle.net/20.500.12008/33428 10.1016/j.virusres.2021.198531 |
| dc.language.none.fl_str_mv | en eng |
| dc.publisher.none.fl_str_mv | Elsevier |
| dc.relation.none.fl_str_mv | Virus Research, 2021, 304: 198531. |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess Licencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0) |
| dc.source.none.fl_str_mv | reponame:COLIBRI instname:Universidad de la República instacron:Universidad de la República |
| dc.subject.none.fl_str_mv | SARS-CoV-2 Alpha variant |
| dc.title.none.fl_str_mv | A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world |
| dc.type.none.fl_str_mv | Artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| description | Since its first detection in the UK in September 2020, a highly contagious version of the coronavirus, the alpha or British variant a.k.a. B.1.1.7 SARS-CoV-2 virus lineage, rapidly spread across several countries and became the dominant strain in the outbreak. Here it is shown that a very simple evolutionary model can fit the observed change in frequency of B.1.1.7 for several countries, regions of countries and the whole world with a single parameter, its relative fitness f, which is almost universal f ≈ 1.5. This is consistent with a 50% higher ransmissibility than the local wild type and with the fact that the period in which this variant takes over has been in all the studied cases around 22 weeks. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | anni_90a679dc0c9cbe012bcdfb30893e1b9e |
| identifier_str_mv | Fort, H. "A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world". Virus Research. [en línea] 2021, 304: 198531. 5 h. Doi: 10.1016/j.virusres.2021.198531. 0168-1702 10.1016/j.virusres.2021.198531 |
| instacron_str | Universidad de la República |
| institution | Universidad de la República |
| instname_str | Universidad de la República |
| language | eng |
| language_invalid_str_mv | en |
| network_acronym_str | anni |
| network_name_str | oai-lr-anni |
| oai_identifier_str | oai:colibri.udelar.edu.uy:20.500.12008/33428 |
| publishDate | 2021 |
| publishDateSort | 2021 |
| publisher.none.fl_str_mv | Elsevier |
| reponame_str | COLIBRI |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | Licencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0) |
| spelling | A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the worldFort, HugoSARS-CoV-2Alpha variantSince its first detection in the UK in September 2020, a highly contagious version of the coronavirus, the alpha or British variant a.k.a. B.1.1.7 SARS-CoV-2 virus lineage, rapidly spread across several countries and became the dominant strain in the outbreak. Here it is shown that a very simple evolutionary model can fit the observed change in frequency of B.1.1.7 for several countries, regions of countries and the whole world with a single parameter, its relative fitness f, which is almost universal f ≈ 1.5. This is consistent with a 50% higher ransmissibility than the local wild type and with the fact that the period in which this variant takes over has been in all the studied cases around 22 weeks.ElsevierFort Hugo, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física.2022-08-30T14:08:18Z2022-08-30T14:08:18Z2021Artículoinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion5 happlication/pdfFort, H. "A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world". Virus Research. [en línea] 2021, 304: 198531. 5 h. Doi: 10.1016/j.virusres.2021.198531.0168-1702https://hdl.handle.net/20.500.12008/3342810.1016/j.virusres.2021.198531reponame:COLIBRIinstname:Universidad de la Repúblicainstacron:Universidad de la RepúblicaenengVirus Research, 2021, 304: 198531.Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014)info:eu-repo/semantics/openAccessLicencia Creative Commons Atribución - No Comercial - Sin Derivadas (CC - By-NC-ND 4.0)oai:colibri.udelar.edu.uy:20.500.12008/334282026-04-14T10:09:55Z |
| spellingShingle | A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world Fort, Hugo SARS-CoV-2 Alpha variant |
| status_str | publishedVersion |
| title | A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world |
| title_full | A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world |
| title_fullStr | A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world |
| title_full_unstemmed | A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world |
| title_short | A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world |
| title_sort | A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world |
| topic | SARS-CoV-2 Alpha variant |
| url | https://hdl.handle.net/20.500.12008/33428 |