In vitro screening of the open-access Pandemic Response Box reveals ESI-09 as a compound with activity against Echinococcus multilocularis

Alveolar echinococcosis (AE) is a life-threatening disease caused by the metacestode stage of the fox tapeworm Echinococcus multilocularis, primarily in the liver. Current drug treatments rely on benzimidazoles, which are not parasiticidal, requiring life-long therapy with significant side effects....

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Bibliographic Details

Main Author:	Zumstein, Pascal (author)
Other Authors:	Bartetzko, Anissa (author), Kaethner, Marc (author), Vetter, Laura (author), Hemphill, Andrew (author), Zumkehr, Trix (author), Laleu, Benoît (author), Preza Pérez, Matías Facundo (author), Lundström-Stadelmann, Britta (author)
Format:	article
Language:	English
Published:	2025
Subjects:	Echinococcus mutlilocularis Alveolar echinococcosis Drug repurposing MMV DNDi Mitochondrial uncoupler
Online Access:	https://hdl.handle.net/20.500.12008/54047
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