Identification of Chalcones as Fasciola hepatica Cathepsin L inhibitors using a comprehensive experimental and computational approach

Background: Increased reports of human infections have led fasciolosis, a widespread disease of cattle and sheep caused by the liver flukes Fasciola hepatica and Fasciola gigantica, to be considered an emerging zoonotic disease. Chemotherapy is the main control measure available, and triclabendazole...

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Bibliographic Details

Main Author:	Ferraro, Florencia (author)
Other Authors:	Merlino Mellognio, Alicia Beatriz (author), Dell'Oca Runco, Nicolás (author), Gil, Jorge (author), Tort, José F. (author), González, Mercedes (author), Cerecetto, Hugo (author), Cabrera Cedrés, Mauricio Andrés (author), Corvo, Ileana (author)
Format:	article
Language:	English
Published:	2016
Subjects:	Fasciolosis Zoonosis Chalcones Fasciola Hepatica
Online Access:	https://hdl.handle.net/20.500.12008/22414
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