Alternative splicing of coq-2 controls the levels of rhodoquinone in animals

Parasitic helminths use two benzoquinones as electron carriers in the electron transport chain. In normoxia, they use ubiquinone (UQ), but in anaerobic conditions inside the host, they require rhodoquinone (RQ) and greatly increase RQ levels. We previously showed the switch from UQ to RQ synthesis i...

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Detalhes bibliográficos

Autor principal:	Tan, June H. (author)
Outros Autores:	Lautens, Margot (author), Romanelli-Cedrez, Laura (author), Wang, Jianbin (author), Schertzberg, Michael R. (author), Reinl, Samantha R. (author), Davis, Richard E. (author), Shepherd, Jennifer N. (author), Fraser, Andrew G. (author), Salinas, Gustavo (author)
Formato:	article
Idioma:	inglês
Publicado em:	2020
Assuntos:	Rhodoquinone Rodoquinona Ubiquinone Ubiquinona C. elegans Electron transport chain Cadena de transporte de electrones Helminth Helmintos Ciencias Naturales y Exactas Ciencias Biológicas Bioquímica y Biología Molecular
Acesso em linha:	https://hdl.handle.net/20.500.12381/3125 https://doi.org/10.7554/eLife.56376
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