Development and Evaluation of 99mTc Tricarbonyl Complexes Derived from Flutamide with Affinity for Androgen Receptor

With the objective to develop a potential 99mTc radiopharmaceutical for imaging the androgen receptor (AR) in prostate cancer, four ligands bearing the same pharmacophore derived from the ARantagonist flutamide were prepared, labeled with 99mTc, and their structures corroborated via comparison with...

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Bibliographic Details

Main Author:	Cardoso, María Elena (author)
Other Authors:	Decuadra, Paula (author), Zeni, Maia (author), Delfino, Agustín (author), Tejería, Emilia (author), Coppe, Fátima (author), Mesa, Juan Manuel (author), Daher, Grysette (author), Giglio, Javier (author), Carrau, Gonzalo (author), Gamenara, Daniela (author), Alonso, Omar (author), Terán, Mariella (author), Rey, Ana (author)
Format:	article
Language:	English
Published:	2023
Subjects:	99mTc Prostate cancer Androgen receptor DIAGNÓSTICO POR IMAGEN FLUTAMIDA FARMACOLOGÍA COMPUESTOS DE ORGANOTECNECIO HOMBRES RADIOFÁRMACOS RECEPTORES ANDROGÉNICOS COMPUESTOS DE TECNECIO NEOPLASIAS DE LA PRÓSTATA
Online Access:	https://hdl.handle.net/20.500.12008/52343
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