Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells

Nuclear lamins support the nuclear envelope and provide anchorage sites for chromatin. They are involved in DNA synthesis, transcription, and replication. It has previously been reported that the lack of Lamin A/C expression in lymphoma and leukaemia is due to CpG island promoter hypermethylation. H...

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Bibliographic Details

Main Author:	Rauschert, Inés (author)
Other Authors:	Aldunate Caramori, Fabián (author), Preussner, J. (author), Arocena, Miguel (author), Peraza Geist, Vanina Mercedes (author), Looso, M. (author), Benech, Juan Claudio (author), Agrelo, Ruben (author)
Format:	article
Language:	English
Published:	2017
Subjects:	Lamin Type A Lamins Syndrome HGPS
Online Access:	https://hdl.handle.net/20.500.12008/22555
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