Potential antimicrobial use of cannabidiol in dentistry: a scoping review.

Background/Objectives: The use of cannabidiol (CBD) as an antimicrobial and antifungal agent has gained interest in medicine, with studies suggesting potential against various microorganisms. However, its effectiveness against oral pathogens remains underexplored in dental research, highlighting the...

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Hovedforfatter: Mederos, Matías (author)
Andre forfattere: Elizalde-Hernández, Alejandro (author), Francia, Alejandro (author), Chisini, Luiz Alexandre (author), Isolan, Cristina Pereira (author), Moraes, Rafael R. (author), Guerra Lund, Rafael (author), David, Carla (author)
Format: article
Sprog:engelsk
Udgivet: 2025
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Online adgang:https://hdl.handle.net/20.500.12008/53559
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author Mederos, Matías
author2 Elizalde-Hernández, Alejandro
Francia, Alejandro
Chisini, Luiz Alexandre
Isolan, Cristina Pereira
Moraes, Rafael R.
Guerra Lund, Rafael
David, Carla
author2_role author
author
author
author
author
author
author
author_browse Chisini, Luiz Alexandre
David, Carla
Elizalde-Hernández, Alejandro
Francia, Alejandro
Guerra Lund, Rafael
Isolan, Cristina Pereira
Mederos, Matías
Moraes, Rafael R.
author_facet Mederos, Matías
Elizalde-Hernández, Alejandro
Francia, Alejandro
Chisini, Luiz Alexandre
Isolan, Cristina Pereira
Moraes, Rafael R.
Guerra Lund, Rafael
David, Carla
author_role author
collection COLIBRI
dc.contributor.none.fl_str_mv Mederos Matías, Universidad de la República (Uruguay). Facultad de Odontología.
Elizalde-Hernández Alejandro, Universidad Federal de Pelotas (Brasil).
Francia Alejandro, Universidad de la Repúbica (Uruguay). Facultad de Odontología. Departamento de Biología Odontológica.
Chisini Luiz Alexandre, Universidad Federal de Pelotas (Brasil).
Isolan Cristina Pereira, Universidad Federal de los Valles de Jequitinhonha y Mucuri
Moraes Rafael R., Universidad Federal de Pelotas (Brasil).
Guerra Lund Rafael, Universidad Federal de Pelotas (Brasil).
David Carla, Universidad Federal de Pelotas (Brasil).
dc.creator.none.fl_str_mv Mederos, Matías
Elizalde-Hernández, Alejandro
Francia, Alejandro
Chisini, Luiz Alexandre
Isolan, Cristina Pereira
Moraes, Rafael R.
Guerra Lund, Rafael
David, Carla
dc.date.none.fl_str_mv 2025
2026-02-23T17:21:38Z
2026-02-23T17:21:38Z
dc.format.none.fl_str_mv 19 h.
application/pdf
dc.identifier.none.fl_str_mv Mederos, M, Elizalde-Hernández, A, Francia, A, [y otros autores]. "Potential antimicrobial use of cannabidiol in dentistry: a scoping review". Dentistry Journal. [en línea] 2025, 13:519.
2304-6767
https://hdl.handle.net/20.500.12008/53559
10.3390/dj13110519
dc.language.none.fl_str_mv en
eng
dc.publisher.none.fl_str_mv MDPI
dc.relation.none.fl_str_mv Dentistry Journal, 2025, 13:519.
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
Licencia Creative Commons Atribución (CC - By 4.0)
dc.source.none.fl_str_mv reponame:COLIBRI
instname:Universidad de la República
instacron:Universidad de la República
dc.subject.none.fl_str_mv Actividad antibacteriana
Actividad antibiopelícula
Biofilm
PLACA DENTAL
BIOPELICULAS
CANNABIDIOL
dc.title.none.fl_str_mv Potential antimicrobial use of cannabidiol in dentistry: a scoping review.
dc.type.none.fl_str_mv Artículo
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
description Background/Objectives: The use of cannabidiol (CBD) as an antimicrobial and antifungal agent has gained interest in medicine, with studies suggesting potential against various microorganisms. However, its effectiveness against oral pathogens remains underexplored in dental research, highlighting the need for further studies. This scoping review summarizes current evidence on the antimicrobial properties of CBD in dental and oral health. Methods: A systematic search was conducted across seven databases (PubMed, the Cochrane Library, Scopus, Embase,Web of Science, SciELO, and LILACS) up to January 2025. The inclusion criteria encompassed studies that explored the effects of CBD on oral microbiology (in vitro and in vivo in animal models), regardless of language or year of publication. The gray literature was evaluated in the Google Scholar database. Results: A total of 1284 articles were identified, of which 10 met the inclusion criteria for this scoping review. These studies, published between 2019 and 2025, primarily focused on bacterial and fungal cultures. The most commonly used methods were the minimum inhibitory concentration test and counting colony-forming units. The contact methods between CBD and bacterial/fungal cell cultures were either dilution or direct contact. Conclusions: CBD shows promising antimicrobial properties against a range of oral bacteria and fungi, suggesting its potential application in managing oral health conditions.
eu_rights_str_mv openAccess
format article
id anni_3fedbd14ef7c7ad0e5b4fbeaf4eb4f19
identifier_str_mv Mederos, M, Elizalde-Hernández, A, Francia, A, [y otros autores]. "Potential antimicrobial use of cannabidiol in dentistry: a scoping review". Dentistry Journal. [en línea] 2025, 13:519.
2304-6767
10.3390/dj13110519
instacron_str Universidad de la República
institution Universidad de la República
instname_str Universidad de la República
language eng
language_invalid_str_mv en
network_acronym_str anni
network_name_str oai-lr-anni
oai_identifier_str oai:colibri.udelar.edu.uy:20.500.12008/53559
publishDate 2025
publishDateSort 2025
publisher.none.fl_str_mv MDPI
reponame_str COLIBRI
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv Licencia Creative Commons Atribución (CC - By 4.0)
spelling Potential antimicrobial use of cannabidiol in dentistry: a scoping review.Mederos, MatíasElizalde-Hernández, AlejandroFrancia, AlejandroChisini, Luiz AlexandreIsolan, Cristina PereiraMoraes, Rafael R.Guerra Lund, RafaelDavid, CarlaActividad antibacterianaActividad antibiopelículaBiofilmPLACA DENTALBIOPELICULASCANNABIDIOLBackground/Objectives: The use of cannabidiol (CBD) as an antimicrobial and antifungal agent has gained interest in medicine, with studies suggesting potential against various microorganisms. However, its effectiveness against oral pathogens remains underexplored in dental research, highlighting the need for further studies. This scoping review summarizes current evidence on the antimicrobial properties of CBD in dental and oral health. Methods: A systematic search was conducted across seven databases (PubMed, the Cochrane Library, Scopus, Embase,Web of Science, SciELO, and LILACS) up to January 2025. The inclusion criteria encompassed studies that explored the effects of CBD on oral microbiology (in vitro and in vivo in animal models), regardless of language or year of publication. The gray literature was evaluated in the Google Scholar database. Results: A total of 1284 articles were identified, of which 10 met the inclusion criteria for this scoping review. These studies, published between 2019 and 2025, primarily focused on bacterial and fungal cultures. The most commonly used methods were the minimum inhibitory concentration test and counting colony-forming units. The contact methods between CBD and bacterial/fungal cell cultures were either dilution or direct contact. Conclusions: CBD shows promising antimicrobial properties against a range of oral bacteria and fungi, suggesting its potential application in managing oral health conditions.MDPIMederos Matías, Universidad de la República (Uruguay). Facultad de Odontología.Elizalde-Hernández Alejandro, Universidad Federal de Pelotas (Brasil).Francia Alejandro, Universidad de la Repúbica (Uruguay). Facultad de Odontología. Departamento de Biología Odontológica.Chisini Luiz Alexandre, Universidad Federal de Pelotas (Brasil).Isolan Cristina Pereira, Universidad Federal de los Valles de Jequitinhonha y MucuriMoraes Rafael R., Universidad Federal de Pelotas (Brasil).Guerra Lund Rafael, Universidad Federal de Pelotas (Brasil).David Carla, Universidad Federal de Pelotas (Brasil).2026-02-23T17:21:38Z2026-02-23T17:21:38Z2025Artículoinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion19 h.application/pdfMederos, M, Elizalde-Hernández, A, Francia, A, [y otros autores]. "Potential antimicrobial use of cannabidiol in dentistry: a scoping review". Dentistry Journal. [en línea] 2025, 13:519.2304-6767https://hdl.handle.net/20.500.12008/5355910.3390/dj13110519reponame:COLIBRIinstname:Universidad de la Repúblicainstacron:Universidad de la RepúblicaenengDentistry Journal, 2025, 13:519.Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014)info:eu-repo/semantics/openAccessLicencia Creative Commons Atribución (CC - By 4.0)oai:colibri.udelar.edu.uy:20.500.12008/535592026-04-14T10:37:16Z
spellingShingle Potential antimicrobial use of cannabidiol in dentistry: a scoping review.
Mederos, Matías
Actividad antibacteriana
Actividad antibiopelícula
Biofilm
PLACA DENTAL
BIOPELICULAS
CANNABIDIOL
status_str publishedVersion
title Potential antimicrobial use of cannabidiol in dentistry: a scoping review.
title_full Potential antimicrobial use of cannabidiol in dentistry: a scoping review.
title_fullStr Potential antimicrobial use of cannabidiol in dentistry: a scoping review.
title_full_unstemmed Potential antimicrobial use of cannabidiol in dentistry: a scoping review.
title_short Potential antimicrobial use of cannabidiol in dentistry: a scoping review.
title_sort Potential antimicrobial use of cannabidiol in dentistry: a scoping review.
topic Actividad antibacteriana
Actividad antibiopelícula
Biofilm
PLACA DENTAL
BIOPELICULAS
CANNABIDIOL
url https://hdl.handle.net/20.500.12008/53559