The p53 endoplasmic reticulum stress-response pathway evolved in humans but not in mice via PERK-regulated p53 mRNA structures

Cellular stress conditions activate p53-dependent pathways to counteract the inflicted damage. To achieve the required functional diversity, p53 is subjected to numerous post-translational modifications and the expression of isoforms. Little is yet known how p53 has evolved to respond to different s...

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Bibliographic Details

Main Author:	Fusée, L. T. S. (author)
Other Authors:	Salomao, Norman (author), Ponnuswamy, Anand (author), Wang, L. (author), López Ferreira, Luis Ignacio (author), Chen, Sa (author), Gu, Xiaolian (author), Polyzoidis, Stavros (author), Gnanasundram, S (author), Fahraeus, Robin (author)
Format:	article
Language:	English
Published:	2023
Online Access:	https://hdl.handle.net/20.500.12008/43176
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