Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggression

Differences in social status are often mediated by agonistic encounters between competitors. Robust literature has examined social status-dependent brain gene expression profiles across vertebrates, yet social status and reproductive state are often confounded. It has therefore been challenging to i...

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Main Author: Eastman, Guillermo (author)
Other Authors: Valiño Amodio, Guillermo (author), Radío, Santiago (author), Young, R. L. (author), Quintana, Laura (author), Zakon, H. H. (author), Hofmann, H. A. (author), Sotelo-Silveira, José Roberto (author), Silva Barbato, Ana Celia (author)
Format: article
Language:English
Published: 2020
Online Access:https://hdl.handle.net/20.500.12008/30821
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author Eastman, Guillermo
author2 Valiño Amodio, Guillermo
Radío, Santiago
Young, R. L.
Quintana, Laura
Zakon, H. H.
Hofmann, H. A.
Sotelo-Silveira, José Roberto
Silva Barbato, Ana Celia
author2_role author
author
author
author
author
author
author
author
author_browse Eastman, Guillermo
Hofmann, H. A.
Quintana, Laura
Radío, Santiago
Silva Barbato, Ana Celia
Sotelo-Silveira, José Roberto
Valiño Amodio, Guillermo
Young, R. L.
Zakon, H. H.
author_facet Eastman, Guillermo
Valiño Amodio, Guillermo
Radío, Santiago
Young, R. L.
Quintana, Laura
Zakon, H. H.
Hofmann, H. A.
Sotelo-Silveira, José Roberto
Silva Barbato, Ana Celia
author_role author
collection COLIBRI
dc.contributor.none.fl_str_mv Eastman Guillermo, IIBCE
Valiño Amodio Guillermo, IIBCE
Radío Santiago, IIBCE
Young R. L.
Quintana Laura, IIBCE
Zakon H. H.
Hofmann H. A.
Sotelo-Silveira José, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Biología
Silva Barbato Ana Celia, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Biología
dc.creator.none.fl_str_mv Eastman, Guillermo
Valiño Amodio, Guillermo
Radío, Santiago
Young, R. L.
Quintana, Laura
Zakon, H. H.
Hofmann, H. A.
Sotelo-Silveira, José Roberto
Silva Barbato, Ana Celia
dc.date.none.fl_str_mv 2020
2022-02-10T14:53:41Z
2022-02-10T14:53:41Z
dc.format.none.fl_str_mv 11 h.
application/pdf
dc.identifier.none.fl_str_mv Eastman, G, Valiño, G, Radío, S, [y otros] "Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggression". Scientific Reports. [en línea] 2020, 10. 11 h. DOI: 10.1038/s41598-020-66494-9
2045-2322
https://hdl.handle.net/20.500.12008/30821
10.1038/s41598-020-66494-9
dc.language.none.fl_str_mv en
eng
dc.publisher.none.fl_str_mv Nature Research
dc.relation.none.fl_str_mv Scientific Reports, 2020, 10: 9496
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
Licencia Creative Commons Atribución (CC - By 4.0)
dc.source.none.fl_str_mv reponame:COLIBRI
instname:Universidad de la República
instacron:Universidad de la República
dc.title.none.fl_str_mv Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggression
dc.type.none.fl_str_mv Artículo
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
description Differences in social status are often mediated by agonistic encounters between competitors. Robust literature has examined social status-dependent brain gene expression profiles across vertebrates, yet social status and reproductive state are often confounded. It has therefore been challenging to identify the neuromolecular mechanisms underlying social status independent of reproductive state. Weakly electric fish, Gymnotus omarorum, display territorial aggression and social dominance independent of reproductive state. We use wild-derived G. omarorum males to conduct a transcriptomic analysis of non-breeding social dominance relationships. After allowing paired rivals to establish a dominance hierarchy, we profiled the transcriptomes of brain sections containing the preoptic area (region involved in regulating aggressive behaviour) in dominant and subordinate individuals. We identified 16 differentially expressed genes (FDR < 0.05) and numerous genes that co-varied with behavioural traits. We also compared our results with previous reports of differential gene expression in other teleost species. Overall, our study establishes G. omarorum as a powerful model system for understanding the neuromolecular bases of social status independent of reproductive state.
eu_rights_str_mv openAccess
format article
id anni_2e572295ff74224b17c2c91c6fdb9c71
identifier_str_mv Eastman, G, Valiño, G, Radío, S, [y otros] "Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggression". Scientific Reports. [en línea] 2020, 10. 11 h. DOI: 10.1038/s41598-020-66494-9
2045-2322
10.1038/s41598-020-66494-9
instacron_str Universidad de la República
institution Universidad de la República
instname_str Universidad de la República
language eng
language_invalid_str_mv en
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oai_identifier_str oai:colibri.udelar.edu.uy:20.500.12008/30821
publishDate 2020
publishDateSort 2020
publisher.none.fl_str_mv Nature Research
reponame_str COLIBRI
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rights_invalid_str_mv Licencia Creative Commons Atribución (CC - By 4.0)
spelling Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggressionEastman, GuillermoValiño Amodio, GuillermoRadío, SantiagoYoung, R. L.Quintana, LauraZakon, H. H.Hofmann, H. A.Sotelo-Silveira, José RobertoSilva Barbato, Ana CeliaDifferences in social status are often mediated by agonistic encounters between competitors. Robust literature has examined social status-dependent brain gene expression profiles across vertebrates, yet social status and reproductive state are often confounded. It has therefore been challenging to identify the neuromolecular mechanisms underlying social status independent of reproductive state. Weakly electric fish, Gymnotus omarorum, display territorial aggression and social dominance independent of reproductive state. We use wild-derived G. omarorum males to conduct a transcriptomic analysis of non-breeding social dominance relationships. After allowing paired rivals to establish a dominance hierarchy, we profiled the transcriptomes of brain sections containing the preoptic area (region involved in regulating aggressive behaviour) in dominant and subordinate individuals. We identified 16 differentially expressed genes (FDR < 0.05) and numerous genes that co-varied with behavioural traits. We also compared our results with previous reports of differential gene expression in other teleost species. Overall, our study establishes G. omarorum as a powerful model system for understanding the neuromolecular bases of social status independent of reproductive state.Nature ResearchEastman Guillermo, IIBCEValiño Amodio Guillermo, IIBCERadío Santiago, IIBCEYoung R. L.Quintana Laura, IIBCEZakon H. H.Hofmann H. A.Sotelo-Silveira José, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de BiologíaSilva Barbato Ana Celia, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Biología2022-02-10T14:53:41Z2022-02-10T14:53:41Z2020Artículoinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion11 h.application/pdfEastman, G, Valiño, G, Radío, S, [y otros] "Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggression". Scientific Reports. [en línea] 2020, 10. 11 h. DOI: 10.1038/s41598-020-66494-92045-2322https://hdl.handle.net/20.500.12008/3082110.1038/s41598-020-66494-9reponame:COLIBRIinstname:Universidad de la Repúblicainstacron:Universidad de la RepúblicaenengScientific Reports, 2020, 10: 9496Las obras depositadas en el Repositorio se rigen por la Ordenanza de los Derechos de la Propiedad Intelectual de la Universidad de la República.(Res. Nº 91 de C.D.C. de 8/III/1994 – D.O. 7/IV/1994) y por la Ordenanza del Repositorio Abierto de la Universidad de la República (Res. Nº 16 de C.D.C. de 07/10/2014)info:eu-repo/semantics/openAccessLicencia Creative Commons Atribución (CC - By 4.0)oai:colibri.udelar.edu.uy:20.500.12008/308212026-04-14T10:09:46Z
spellingShingle Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggression
Eastman, Guillermo
status_str publishedVersion
title Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggression
title_full Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggression
title_fullStr Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggression
title_full_unstemmed Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggression
title_short Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggression
title_sort Brain transcriptomics of agonistic behaviour in the weakly electric fish Gymnotus omarorum, a wild teleost model of non-breeding aggression
url https://hdl.handle.net/20.500.12008/30821