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Integrating different approaches for the identification of new disruptors of HIV-1 capsid multimerization

Human Immunodeficiency Virus (HIV) belongs to the Lentivirus genus, Retroviridae family, enveloped by a lipid bilayer within which the capsid protein encases the viral genome, reverse transcriptase, and integrase proteins, key components for viral replication. Viral capsid has been linked to key ear...

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Hlavní autor: Artía, Zoraima (author)
Další autoři: Guillon, Christophe (author), Robert, Xavier (author), Granzella, Maximiliano (author), Segovia, Ana Clara (author), Truong, Ha H (author), Álvarez, Guzmán (author), Corvo, Ileana (author), Randall-Carlevaro, Lía (author)
Médium: article
Jazyk:angličtina
Vydáno: 2025
Témata:
Artificial intelligence
Capsid
Drug development
HIV-1
Screening
Ciencias Médicas y de la Salud
Medicina Básica
Bioquímica y Biología Molecular
Medicina Química
Farmacología y Farmacia
On-line přístup:https://hdl.handle.net/20.500.12381/5273
https://doi.org/10.1016/j.bbrc.2025.151572
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