Protein secondary structure determination by constrained single-particle cryo-electron tomography

Cryo-electron microscopy (cryo-EM) is a powerful technique for 3D structure determination of protein complexes by averaging information from individual molecular images. The resolutions that can be achieved with single-particle cryo-EM are frequently limited by inaccuracies in assigning molecular or...

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Bibliographic Details
Main Author: Subramanian, Sriram (author)
Other Authors: Sapiro, Guillermo (author), Lecumberry, Federico (author), Bartesaghi, Alberto (author)
Format: article
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/20.500.12008/41130
https://doi.org/10.1016/j.str.2012.10.016
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