An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency

Sumoylation is an essential posttranslational modification in eukaryotes that has emerged as an important pathway in oncogenic processes. Most human cancers display hyperactivated sumoylation and many cancer cells are remarkably sensitive to its inhibition, thus supporting application of chemical su...

Descripción completa

Detalles Bibliográficos

Autor principal:	López Ferreira, Luis Ignacio (author)
Otros Autores:	Chalatsi, E. (author), Ellenbroek, S. I. J. (author), Andrieux, A. (author), Roux, P. F. (author), Cerapio, J. P. (author), Jouvion, G. (author), van Rheenen, J. (author), Seeler, J. S. (author), Dejean, A. (author)
Formato:	article
Lenguaje:	inglés
Publicado:	2020
Acceso en línea:	https://hdl.handle.net/20.500.12008/30861
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!