Recombinant antibody against Trypanosoma cruzi from patients with chronic Chagas heart disease recognizes mammalian nervous system.

Background: To deeply understand the role of antibodies in the context of Trypanosoma cruzi infection, we decided to characterize A2R1, a parasite antibody selected from single-chain variable fragment (scFv) phage display libraries constructed from B cells of chronic Chagas heart disease patients. M...

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Bibliographic Details

Main Author:	Niborski, Leticia L. (author)
Other Authors:	Potenza, Mariana (author), Chirivi, Renato G. S. (author), Simonetti, Leandro (author), Ossowski, Micaela S. (author), Grippo, Vanina (author), May, Maria (author), Staquicini, Daniela I. (author), Parodi-Tálice, Adriana Magdalena (author), Robello Porto, Carlos (author), Comini, Marcelo A. (author), Alonso, Guillermo D. (author), Raats, Jos M.H. (author), Gómez, Karina A. (author)
Format:	article
Language:	English
Published:	2021
Subjects:	Chagas disease Phage-display Tubulin Molecular mimicry Post-translational modification Digestive system
Online Access:	https://hdl.handle.net/20.500.12008/33236
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